drugtarget相关论文
Structural overview and perspectives of the nuclear receptors,a major family as the direct targets f
The nuclear receptors(NRs)are an evolutionarily related family of transcription factors,which share certain common struc......
目的 Knowledge of the molecular mechanisms on malignant tumors is very critical for the development of new treatmentstra......
Natural Product Bufalin Blocks Hepatocellular Carcinoma Proliferation and Migration by Targeting Mem
Bufalin,a main components of traditional chinese medicine from toad venom,is widely used to treat a variety of cancers i......
The identification of interaction between drugs and target proteins is a key area in drug discovery [1].The adrenergic r......
Anti-influenza drugs are one of the most critical pathways for control of influenza virus infection. Drugs that have bee......
Compared to the great achievement in the development of anti-malarial drugs based on the natural product artemisinin......
Background: Post-translational modification (PTM) is one of the most important biological processes within cellular ......
Genetic and structural validation of enyzmes required for activation of UDP-GlcNAc in Aspergillus fu
...
Inflammation and dysregulation of immune response in Alzheimer disease,the drug target for the futur
It has been demonstrated that inflammation and dysregulation of immune response are involved in the pathogenesis of ......
The β‐secretase,β‐site amyloid precursor protein(APP)cleaving enzyme 1(BACE1),is the first of two proteases(the ......
Schistosomiasis is a neglected parasitic disease with high morbidity and mortality.Currently, the treatment of this ......
目的探讨间羟胺依照目标剂量靶控输注对老年人腰硬联合麻醉髋关节手术后意识（认知功能）的影响。方法：择期行髋关节手术老年病人40例，年......
沉默信息调节因子2相关酶1（Sirt1）是一种依赖于烟酰胺腺嘌呤二核苷酸的Ⅲ类组蛋白脱乙酰化酶，为哺乳动物Sirtuin家族成员之一。 Sirt1......
随着人类基因线计划的实施将会发现越来越多的功能基因。从中了解到的生物信息对我们了解发病机制将提供很大的帮助，同时可进行广泛......
